Digit Amputation


Article Author:
Lihan Zhang


Article Editor:
Clifford Buckley


Editors In Chief:
Shivajee Nallamothu
Matthew Varacallo
Joshua Tuck


Managing Editors:
Orawan Chaigasame
Carrie Smith
Abdul Waheed
Frank Smeeks
Kristina Soman-Faulkner
Benjamin Eovaldi
Radia Jamil
Sobhan Daneshfar
Saad Nazir
William Gossman
Pritesh Sheth
Hassam Zulfiqar
Navid Mahabadi
Steve Bhimji
John Shell
Matthew Varacallo
Ahmad Malik
Mark Pellegrini
James Hughes
Beata Beatty
Hajira Basit
Phillip Hynes


Updated:
4/1/2019 5:06:37 PM

Introduction

Digital amputation is often associated with traumatic injuries but is also seen within the elective surgery setting, such as cancer resection and management of chronic conditions such as Dupuytren's contractures or peripheral vascular disease. It is also seen as a consequence of severe sepsis, although this often results in auto-amputation. 

In the traumatic setting, the primary objective of management is to salvage the amputated finger to restore function, especially if the dominant hand is affected. However, this is not always possible, as there are many factors to consider.  These factors include the time from injury, mechanism of injury, and degree of contamination [1]. In the elective setting, determinants for the level of amputation include various factors, such as oncological clearance, symptom relief, and function preservation; however, for the purpose of this paper, the primary focus will be on traumatic finger amputation. 

Etiology

In traumatic injuries, one should assess the patient in accordance with the Advanced Trauma Life Support approach (Airway, Breathing, Circulation, etc.) for a systematic assessment of the patient and to rule out any life-threatening injuries before referring or transferring patients for further specialist management of their finger injuries. Determining the mechanism of injury is crucial, as it could affect decisions regarding management and outcome for the patient.  Sharp injuries may provide a clear amputation level, whereas blunt trauma may correlate with crush injuries at the level of the amputation, and avulsion injuries can cause distant trauma away from the level of visible injury.

Epidemiology

Amputation injuries represent approximately 1% of all trauma-related injuries presenting to the emergency department, with finger and thumb amputations being the most common.[1] Fingertip and partial digit amputation are the most frequent presentations, complete digit and multiple digit amputations are less common, with most injuries occurring at home.[2] Its incidence is higher in adults (men greater than women, approximately 4 to 1) than children (approximately 3 to 1 adult to child ratio). Working with power tools is the most common cause of injury in adults.

Pathophysiology

Typically, once a finger amputation has occurred, ischemic tolerance times are 12 hours if warm and up to 24 hours if cold. For more proximal amputations, these times are halved. The amputated part should be covered in a normal saline soaked gauze, sealed in a plastic bag and submerged in icy water with no direct contact with ice. If there is direct contact with ice, it could result in tissue damage and render the amputated part non-viable. More proximal amputations are less tolerant of ischemia due to the presence of muscle tissue, which can undergo irreversible changes after 6 hours of ischemia.[3][4]

History and Physical

History:

Hand dominance, occupation, time of injury, mechanism of injury, other associated injuries, comorbidities and NPO status.

Physical Exam:

Level of amputation, structures involved, neurovascular status, function, and degree of contamination (if relevant).  It is vital to assess the amputated part and ultimately determine its suitability for replanting respective to the mechanism of injury (e.g., crush, guillotine-style, avulsion).

Finger amputations classification is generally according to the level of amputation.  The Sebastian and Chung classification is outlined below[5]:

  • Zone 1 distal amputations 
    • Zone 1A - distal to lunula, through the sterile matrix
    • Zone 1B - between lunula and nailbed
  • Zone 1 proximal amputations
    • Zone 1C - between flexor digitorum profundus insertion and neck of the middle phalanx
    • Zone 1D - between the neck of the middle phalanx and insertion of the flexor digitorum superficialis

Evaluation

Laboratory:(optional depending on clinical scenario)

CBC (complete blood count) to assess for blood loss

Coagulation studies (only if the patient is known to be on anticoagulants)

Imaging:

Plain radiograph of the affected finger/hand and amputated part; this allows assessment of bony injuries, bone quality and guide decisions regarding bony fixation methods. Angiograms are normally not requested unless it forms part of investigations for other injuries.

Treatment / Management

Initial management - first aid, ATLS approach to the patient, preserve amputated part, tetanus vaccination, and antibiotics as per local hospital guidelines.

In the traumatic setting, the ideal candidate for replantation should be young, healthy, sharp mechanism of injury (giving a clear amputation level), minimal tissue destruction and contamination.[3]

Indications for replantation[1][3]:

  • Thumb amputation - loss of thumb represent approximately 40 to 50% loss of hand function
  • Multiple finger amputations
  • Amputations at or proximal to palm
  • Pediatric patients with finger amputation(s) at any level
  • Single finger amputation distal to insertion of the flexor digitorum superficialis (zone I) (studies have shown that replantation distal to this insertion point had better outcomes than those proximal)
  • Patient consideration - specialist requirement, e.g., occupation or pre-morbid compromised hand function

Contraindications and relative contraindications[3]:

  • Single digit injury through flexor tendon zone II
  • Smoking
  • Severe crush
  • Mangled limb
  • Heavy contamination
  • Segmental injuries
  • Prolonged warm ischaemic time
  • Medically unfit
  • Improperly preserved amputated part
  • Avulsion injuries 
  • Other life-threatening injuries
  • Mentally unstable
  • Previous surgery to affected finger 
  • 'Red line' or 'red ribbon' sign (seen in vessels during surgery), which predicts the level of intimal damage in the vessel

Once the patient arrives in the operating theater, the amputated part should undergo a careful assessment for suitability for replanting. All structures should be dissected and identified, especially the neurovascular bundle. If no suitable vessels are identified, then replantation should not proceed. Usually, there is an order for repair of structures:

  1. Bone fixation with or without bone shortening to allow repair of soft tissue
  2. Tendon repair - extensor and flexor tendons
  3. Nerve repair
  4. Arterial anastomosis
  5. Venous anastomosis (if suitable veins are present)

Bone fixation should be simple and quick to perform, but it also depends on the configuration of bony injuries. Usually, two Kirschner wires are an option, but other fixation methods may also be used (i.e., plate fixation). Occasionally, bone shortening is required before fixation to allow for soft tissue closure and repair of neurovascular structures without excessive tension. 

Differential Diagnosis

Digit amputations tend to be a straight forward presentation, but infectious processes can mimic amputation leading to loss of fingers/toes. 

Prognosis

Previous studies have found these factors to have a substantial effect on functional outcome[6]:

  1. Level of the amputation
  2. Number of fingers injured
  3. Circumstance and mechanism surround injury
  4. Time from injury

Survival rates following replantation have been reported between 80 to 90%, although these figures have come from specialist institutions. It is also worth noting that venous repair improves survival regardless of the level of amputation. This fact is important, as venous repair is not always possible, and as a result, it could lead to venous congestion.  One solution would be to make a small distal incision to allow venous drainage or the use of leeches. 

Complications

Complications classify according to the time of onset[1]

  • Early complications
    • Arterial insufficiency
      • Arterial thrombosis presents typically as a pale, cool and pulseless digit
      • It is vital during the post-operative period to maximize blood flow through the anastomoses and prevent thrombosis
    • Venous insufficiency
      • Venous congestion typically presents as a purple digit with brisk capillary refill and swelling
      • Concerns of possible anastomosis failure or thrombosis should prompt urgent return to theatre for salvage - in cases of venous congestion, leech therapy or anticoagulation may be considered to improve venous return
    • Infection
  • Late complications
    • Cold intolerance
    • Tendon adhesions
    • Stiffness
    • Bony malunion
    • Altered sensation

Postoperative and Rehabilitation Care

Post-operative management:

  • Maintain adequate hydration and circulation volume
  • Analgesia
  • Keep the affected limb elevated and warm
  • Frequent monitoring of the replant capillary refill, color, and temperature
  • Avoid dressings changes in the first 48 to 72 hours to minimize manipulation of the repair
  • Consider anticoagulation
  • In cases of artery-only replants, consider stab incision to the distal amputated tip and apply heparin soaked gauze to allow venous drainage or use leeches instead. This treatment can end once the finger becomes pink with normal capillary refill thus indicating adequate venous drainage

Some patients require further surgery to improve their function, such as tenolysis, bone grafting, tendon transfer, etc.[1] On average, following upper limb amputations, patients return to work within 2 to 3 months after injury.[1] Studies show that functional recovery is better in more distal injuries than proximal, both in terms of movement and power.[6]

Deterrence and Patient Education

  • Good health and safety regulations - to provide a safe working environment and reduce occupation-related injuries
  • Public information leaflet/public awareness campaign - same objective as above, but to ensure a safe home environment for work and recreation, e.g., BBC News article in May 2018, warning the public of DIY and gardening accidents 

Pearls and Other Issues

  • Once a patient with an amputation injury arrives in hospital, a speedy but thorough assessment is essential to minimize the delay to definitive surgical management
  • Often, amputated parts are brought to the emergency department (although sometimes forgotten at the scene or referring hospital) in inappropriate storage. As a specialist center, it is crucial to inform referring units of the best way to preserve the amputated part, to label it with the patient's details and keep it with the patient to avoid loss
  • Early involvement of specialists where possible
  • Take account of patient factors, i.e., age, occupation, comorbidities, and also patient wishes - replantation requires long and complex surgery, hospital admission, the risk of complications, long rehabilitation, and risk of an incomplete return to normal function. 
    • This may not be acceptable in some patients, especially in those who are self-employed and cannot take prolonged time off work
    • As such, terminalization of the affected finger may allow early return to work and normal function for the patient - if possible, the patient needs to understand their options and the potential outcome of each
  • Good rehabilitation process - early involvement of hand therapists

Enhancing Healthcare Team Outcomes

Surgical replantation requires a multi-professional approach. In terms of surgery, specialist surgeon(s) would be required to perform the procedure efficiently and effectively.  During the recovery period, skilled nursing care experienced in follow-up care of patients with amputations is vital to ensure good monitoring of the replant, and allow early detection of pending complications. Early involvement of an occupational hand therapists is also vital (some say the most important part) to patient recovery and the return of normal function. 

Evidence generally shows good outcome in distal amputations, especially if venous repair is possible. However, the evidence is limited in patients who do not proceed to replant.

Even after the replantation, patients often require an extensive interprofessional rehabilitation effort of nurses, occupational therapists, and physical rehabilitation physicians to regain function of the digit.


Interested in Participating?

We are looking for contributors to author, edit, and peer review our vast library of review articles and multiple choice questions. In as little as 2-3 hours you can make a significant contribution to your specialty. In return for a small amount of your time, you will receive free access to all content and you will be published as an author or editor in eBooks, apps, online CME/CE activities, and an online Learning Management System for students, teachers, and program directors that allows access to review materials in over 500 specialties.

Improve Content - Become an Author or Editor

This is an academic project designed to provide inexpensive peer-reviewed Apps, eBooks, and very soon an online CME/CE system to help students identify weaknesses and improve knowledge. We would like you to consider being an author or editor. Please click here to learn more. Thank you for you for your interest, the StatPearls Publishing Editorial Team.

Digit Amputation - Questions

Take a quiz of the questions on this article.

Take Quiz
Which of the following digit injuries has the best success for replanting?



Click Your Answer Below


Would you like to access teaching points and more information on this topic?

Improve Content - Become an Author or Editor and get free access to the entire database, free eBooks, as well as free CME/CE as it becomes available. If interested, please click on "Sign Up" to register.

Purchase- Want immediate access to questions, answers, and teaching points? They can be purchased above at Apps and eBooks.


Sign Up
Which of the following is not a significant factor which impairs replantation of an amputated digit?



Click Your Answer Below


Would you like to access teaching points and more information on this topic?

Improve Content - Become an Author or Editor and get free access to the entire database, free eBooks, as well as free CME/CE as it becomes available. If interested, please click on "Sign Up" to register.

Purchase- Want immediate access to questions, answers, and teaching points? They can be purchased above at Apps and eBooks.


Sign Up
Which of the following treatments is reasonable following an avulsion amputation of the index finger through the proximal phalanx?



Click Your Answer Below


Would you like to access teaching points and more information on this topic?

Improve Content - Become an Author or Editor and get free access to the entire database, free eBooks, as well as free CME/CE as it becomes available. If interested, please click on "Sign Up" to register.

Purchase- Want immediate access to questions, answers, and teaching points? They can be purchased above at Apps and eBooks.


Sign Up
What is the proper treatment for an accidentally amputated toe?



Click Your Answer Below


Would you like to access teaching points and more information on this topic?

Improve Content - Become an Author or Editor and get free access to the entire database, free eBooks, as well as free CME/CE as it becomes available. If interested, please click on "Sign Up" to register.

Purchase- Want immediate access to questions, answers, and teaching points? They can be purchased above at Apps and eBooks.


Sign Up
Under most conditions, a patient having an amputation of a digit for gangrene should be placed on antibiotics postoperatively. For which of the following situations are antibiotics not needed?



Click Your Answer Below


Would you like to access teaching points and more information on this topic?

Improve Content - Become an Author or Editor and get free access to the entire database, free eBooks, as well as free CME/CE as it becomes available. If interested, please click on "Sign Up" to register.

Purchase- Want immediate access to questions, answers, and teaching points? They can be purchased above at Apps and eBooks.


Sign Up
Which of the following conditions is NOT an indication for digit amputation?



Click Your Answer Below


Would you like to access teaching points and more information on this topic?

Improve Content - Become an Author or Editor and get free access to the entire database, free eBooks, as well as free CME/CE as it becomes available. If interested, please click on "Sign Up" to register.

Purchase- Want immediate access to questions, answers, and teaching points? They can be purchased above at Apps and eBooks.


Sign Up
A patient with diabetes mellitus is being assessed for digit amputation. Which of the following would not be an appropriate laboratory or diagnostic test to assess surgical site healing potential?



Click Your Answer Below


Would you like to access teaching points and more information on this topic?

Improve Content - Become an Author or Editor and get free access to the entire database, free eBooks, as well as free CME/CE as it becomes available. If interested, please click on "Sign Up" to register.

Purchase- Want immediate access to questions, answers, and teaching points? They can be purchased above at Apps and eBooks.


Sign Up

Digit Amputation - References

References

Win TS,Henderson J, Management of traumatic amputations of the upper limb. BMJ (Clinical research ed.). 2014 Feb 10     [PubMed]
Reavey PL,Stranix JT,Muresan H,Soares M,Thanik V, Disappearing Digits: Analysis of National Trends in Amputation and Replantation in the United States. Plastic and reconstructive surgery. 2018 Jun     [PubMed]
Maricevich M,Carlsen B,Mardini S,Moran S, Upper extremity and digital replantation. Hand (New York, N.Y.). 2011 Dec     [PubMed]
Sebastin SJ,Chung KC, A systematic review of the outcomes of replantation of distal digital amputation. Plastic and reconstructive surgery. 2011 Sep     [PubMed]
Sagiv P,Shabat S,Mann M,Ashur H,Nyska M, Rehabilitation process and functional results of patients with amputated fingers. Plastic and reconstructive surgery. 2002 Aug     [PubMed]
Wolfe VM,Wang AA, Replantation of the upper extremity: current concepts. The Journal of the American Academy of Orthopaedic Surgeons. 2015 Jun     [PubMed]

Disclaimer

The intent of StatPearls is to provide practice questions and explanations to assist you in identifying and resolving knowledge deficits. These questions and explanations are not intended to be a source of the knowledge base of all of medicine, nor is it intended to be a board or certification review of Surgery-Orthopaedic. The authors or editors do not warrant the information is complete or accurate. The reader is encouraged to verify each answer and explanation in several references. All drug indications and dosages should be verified before administration.

StatPearls offers the most comprehensive database of free multiple-choice questions with explanations and short review chapters ever developed. This system helps physicians, medical students, dentists, nurses, pharmacists, and allied health professionals identify education deficits and learn new concepts. StatPearls is not a board or certification review system for Surgery-Orthopaedic, it is a learning system that you can use to help improve your knowledge base of medicine for life-long learning. StatPearls will help you identify your weaknesses so that when you are ready to study for a board or certification exam in Surgery-Orthopaedic, you will already be prepared.

Our content is updated continuously through a multi-step peer review process that will help you be prepared and review for a thorough knowledge of Surgery-Orthopaedic. When it is time for the Surgery-Orthopaedic board and certification exam, you will already be ready. Besides online study quizzes, we also publish our peer-reviewed content in eBooks and mobile Apps. We also offer inexpensive CME/CE, so our content can be used to attain education credits while you study Surgery-Orthopaedic.