Microdermabrasion


Article Author:
Muneeb Shah


Article Editor:
Jonathan Crane


Editors In Chief:
Brian Downs
Ziad Katrib


Managing Editors:
Avais Raja
Orawan Chaigasame
Khalid Alsayouri
Kyle Blair
Radia Jamil
Erin Hughes
Patrick Le
Anoosh Zafar Gondal
Saad Nazir
William Gossman
Hassam Zulfiqar
Navid Mahabadi
Hussain Sajjad
Steve Bhimji
Muhammad Hashmi
John Shell
Matthew Varacallo
Heba Mahdy
Ahmad Malik
Abbey Smiley
Sarosh Vaqar
Mark Pellegrini
James Hughes
Beenish Sohail
Hajira Basit
Phillip Hynes
Sandeep Sekhon


Updated:
9/18/2019 6:09:48 PM

Introduction

Microdermabrasion (MDA) is a minimally invasive epidermal resurfacing procedure used to treat uneven skin tone/texture, photoaging, striae, melasma, and scars, including acne scars. It is widely available and one of the most common nonsurgical cosmetic procedures performed in the United States. MDA was first introduced in 1985 by Marini and Lo Brutto as a less aggressive alternative to chemical peels and dermabrasion. The MDA procedure can be performed in the outpatient setting (medical office, medical spa) by an aesthetician, medical assistant, or nurse without the use of anesthesia.

During the procedure, abrasive crystals are propelled against the skin under the control of a handheld vacuum system. The crystals cause gentle mechanical abrasion to the skin, which ultimately removes the stratum corneum layer of the epidermis. As part of the wound healing process, new epidermis forms with enhanced cosmesis. The technique is considered safe for all Fitzpatrick skin types and complications are minimal. In addition to the cosmetic benefits of MDA, studies have also shown improved skin permeability, and enhanced delivery of transdermal medications dosed on an area of the skin treated with MDA. 

Anatomy

There are five layers of the epidermis, each with different properties (from superficial to deep): 

  • Stratum corneum 
  • Stratum lucidum 
  • Stratum granulosum 
  • Stratum spinosum 
  • Stratum basale

Microdermabrasion removes the stratum corneum, the outermost layer of the epidermis.[1][2][3] MDA has also been shown to affect deeper layers of the epidermis and dermis. MDA causes a re-arrangement of melanosomes in the basal layer of the epidermis, flattening of rete ridges at the dermal-epidermal junction, increased collagen fiber density at the dermal-epidermal junction, and vascular ectasia in the reticular dermis.[4] MDA also causes an upregulation of wound healing transcription factors and matrix metalloproteinases in the dermis.[5]

Indications

Cosmetic indications:[1][4][5][6][7][8]

  • Scars, including acne scars
  • Acne
  • Uneven skin tone/texture
  • Striae distensae (stretch marks) 
  • Melasma
  • Photoaging
  • Seborrheic skin
  • Fine wrinkles
  • Enlarged pores

Patients often report improved skin "glow," softness, texture, and decreased visibility of pores.[1] Decreased sebum levels are noted immediately after the procedure.[8] Biomechanical analysis demonstrates a decrease in skin stiffness, an increase in skin compliance, and an increase in skin thickness.[9] In individuals with melasma, MDA decreases melanization and evenly distributes melanosomes in the epidermis. In individuals with scarring, striae, and photoaging, MDA improves collagen fiber density and distribution. 

Transdermal drug delivery:

Microdermabrasion has been shown to improve transdermal drug delivery by removing the stratum corneum. Methods to increase transdermal delivery often target the stratum corneum layer of the epidermis, as the stratum corneum is the principal barrier that limits the percutaneous diffusion of molecules.[10] Drugs diffuse more freely in the viable epidermis, directly below the stratum corneum layer. MDA has been shown to improve transdermal insulin delivery, transdermal vitamin C delivery, transdermal lidocaine delivery, and transdermal 5-fluorouracil delivery.[11][12][13] Although there are several ongoing clinical trials with promising results, the feasibility of using MDA in a clinical setting to enhance transdermal drug delivery is still unknown.[12]

Contraindications

Microdermabrasion is contraindicated in an area of active cutaneous infection, such as herpes simplex virus, varicella-zoster virus, human papillomavirus, and impetigo.[14] In individuals with contact allergies to the abrasive crystals (i.e., aluminum allergy), a different crystal or a crystal-free system should be used.[15] MDA should be used cautiously in individuals with a known history of hypertrophic scarring (keloids).[8] Rosacea and telangiectasias are considered relative contraindications.[14]

Equipment

Microdermabrasion devices are categorized as either crystal or crystal-free systems. The crystal-based system propels abrasive crystals at the skin at a predetermined flow rate. The most common crystal used is aluminum oxide. Sodium chloride, magnesium oxide, and sodium bicarbonate crystals are less commonly employed. With the crystal-free systems, diamonds embedded in the handpiece provide the abrasive stimulus. The following equipment is needed to perform the procedure: 

  • Microdermabrasion handpiece 
  • Disposable handpiece tips or autoclave-safe handpiece tips
  • Fresh abrasion crystals (for crystal-based systems)
  • Filters (for machines with a closed-loop vacuum system)
  • Gentle skin cleanser 
  • Protective equipment (eyewear, gloves, mask) 

Technique

The area of desired treatment should be cleaned with a mild cleanser prior to the start of the procedure. Moist gauze is placed over the eyes to prevent contact with the abrasive crystals. Contact is made between the skin and the device tip. Using negative pressure, the device pulls the skin into the handpiece. The device then releases the abrasive crystals at a controlled flow rate. Surface debris and the stratum corneum layer of cells are removed, and the particles collect in a reservoir. The device is then passed over the skin to target the desired surface area. A single treatment usually requires three passes over the treated area. Remaining crystals and debris are wiped away with a washcloth, and a gentle moisturizer is applied. The entire procedure typically takes 30-60 minutes. Patients often require 4-6 weekly treatments to achieve the desired results. The degree of stratum corneum removal is dependent on the crystal flow rate and procedure exposure time. The pressure generated by the vacuum device has little effect on stratum corneum removal.[2][9]

Complications

Side effects of microdermabrasion are minimal, and most patients experience no adverse events. Common complications include tenderness, swelling, redness, petechiae, and bruising. Eye irritation can occur if the crystals come in contact with the conjunctiva.[4] There is an increased risk of autoinoculation of viral cutaneous lesions (e.g., molluscum contagiosum) and reactivation of latent herpes simplex virus in an affected dermatome.[9] Since stratum corneum removal occurs during MDA, the skin is more sensitive to photodamage for a few days after treatment. 

Enhancing Healthcare Team Outcomes

Microdermabrasion may be performed by several types of practitioners in the outpatient setting, including aestheticians, medical assistants, and nurses. Although MDA is a relatively benign procedure with minimal complications, all providers should receive training on the benefits as well as risks of the procedure, and proper safety techniques. A medical history, including allergies, should be documented prior to starting the procedure. Appropriate expectations should be set, and patients informed that several treatments might be required to achieve the desired results. As some patients may experience petechiae and redness immediately after the procedure, treatments should be avoided for at least two weeks prior to significant life events (e.g., wedding photography, etc.) Proper sterilization of MDA equipment is essential to prevent infectious disease transmission from one patient to another. Patients should be advised to use sunscreen when outdoors for at least one week following the procedure. For individuals with skin conditions not amenable to MDA, a referral to a dermatologist is in order. 


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Microdermabrasion - Questions

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A 30-year-old woman presents for the management of acne scars. She desires treatment with microdermabrasion. She has a history of diabetes mellitus. She reports contact allergies to nickel and aluminum. Her vital signs are within normal limits. Physical examination reveals scars involving the forehead and both cheeks. Which of the following is the next best step in management?



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A 42-year-old woman comes to the clinic desiring treatment for burn scars. She sustained a third-degree burn to her left face several years ago. She currently takes no medications. Physical examination reveals deep scars affecting the left side of her face. She inquires about microdermabrasion for the treatment of her scars. Which of the following is the next best step in management?



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A 22-year-old female presents for the management of old acne scars and uneven skin tone. She desires treatment with microdermabrasion. She has a history of herpes simplex virus and takes acyclovir daily. Her vital signs are within normal limits. The physical examination reveals scattered acne scars on both cheeks and small fluid-filled vesicles on an erythematous base involving the philtrum. What is the best next step in management?



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A 38-year-old female presents for the management of an uneven skin tone. She desires treatment with microdermabrasion. She has a history of herpes simplex virus well controlled with acyclovir. Her vital signs are within normal limits. The physical examination reveals scattered acne scars on both cheeks and 1 cm honey-crusted lesions affecting the chin. What is the best next step in management?



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A 38-year-old female presents for the management of melasma. She desires treatment with microdermabrasion. She has a history of herpes labialis. Her vital signs are within normal limits. The physical examination reveals flat brown patches involving her left cheek. She undergoes treatment with microdermabrasion, which improves the appearance of her melasma. Which of the following is the most likely mechanism of this treatment?



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A 23-year-old lady with confirmed stable vitiligo lesions not responding to medical or phototherapy has been planned for surgical repigmentation using the Jodhpur technique. The clinic uses mupirocin cream usually which is currently out of stock. The surgical nurse hands over a fresh tube of 2% fusidic acid ointment to the proceduralist instead. What is the most likely expected change in the outcome of the Jodhpur technique grafting if 2% fusidic acid ointment is used instead of mupirocin?



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Microdermabrasion - References

References

Grimes PE, Microdermabrasion. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2005 Sep     [PubMed]
Salik E,Løvik I,Andersen KE,Bygum A, Persistent Skin Reactions and Aluminium Hypersensitivity Induced by Childhood Vaccines. Acta dermato-venereologica. 2016 Nov 2     [PubMed]
Andrews SN,Zarnitsyn V,Bondy B,Prausnitz MR, Optimization of microdermabrasion for controlled removal of stratum corneum. International journal of pharmaceutics. 2011 Apr 4     [PubMed]
El-Domyati M,Hosam W,Abdel-Azim E,Abdel-Wahab H,Mohamed E, Microdermabrasion: a clinical, histometric, and histopathologic study. Journal of cosmetic dermatology. 2016 Dec     [PubMed]
Lee AR,Tojo K, Characterization of skin permeation of vitamin C: theoretical analysis of penetration profiles and differential scanning calorimetry study. Chemical     [PubMed]
Lee WR,Shen SC,Kuo-Hsien W,Hu CH,Fang JY, Lasers and microdermabrasion enhance and control topical delivery of vitamin C. The Journal of investigative dermatology. 2003 Nov     [PubMed]
Andrews S,Lee JW,Choi SO,Prausnitz MR, Transdermal insulin delivery using microdermabrasion. Pharmaceutical research. 2011 Sep     [PubMed]
Prausnitz MR,Langer R, Transdermal drug delivery. Nature biotechnology. 2008 Nov     [PubMed]
Kołodziejczak A,Wieczorek A MSc,Rotsztejn H PhD, The assessment of the effects of the combination of microdermabrasion and cavitation peeling in the therapy of seborrhoeic skin with visible symptoms of acne punctata. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. 2018 Oct 9     [PubMed]
Lloyd JR, The use of microdermabrasion for acne: a pilot study. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2001 Apr     [PubMed]
Tan MH,Spencer JM,Pires LM,Ajmeri J,Skover G, The evaluation of aluminum oxide crystal microdermabrasion for photodamage. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2001 Nov     [PubMed]
Karimipour DJ,Kang S,Johnson TM,Orringer JS,Hamilton T,Hammerberg C,Voorhees JJ,Fisher G, Microdermabrasion: a molecular analysis following a single treatment. Journal of the American Academy of Dermatology. 2005 Feb     [PubMed]
Gill HS,Andrews SN,Sakthivel SK,Fedanov A,Williams IR,Garber DA,Priddy FH,Yellin S,Feinberg MB,Staprans SI,Prausnitz MR, Selective removal of stratum corneum by microdermabrasion to increase skin permeability. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2009 Sep 10     [PubMed]
Karimipour DJ,Karimipour G,Orringer JS, Microdermabrasion: an evidence-based review. Plastic and reconstructive surgery. 2010 Jan     [PubMed]
Alkhawam L,Alam M, Dermabrasion and microdermabrasion. Facial plastic surgery : FPS. 2009 Dec     [PubMed]

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