Monosynaptic Reflex

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Aaron Walkowski

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Sunil Munakomi

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Phillip Hynes

5/3/2019 9:40:38 AM


The monosynaptic stretch reflex, or sometimes also referred to as the muscle stretch reflex, deep tendon reflex, is a reflex arc that provides direct communication between sensory and motor neurons innervating the muscle. This reflex begins inside the muscle spindle of the muscle, which detects both the amount and rate of muscle stretch. When the muscle is stretched, sensory impulses are transmitted from the muscle spindle via Ia afferent fibers to the dorsal root of the spinal cord. Once in the dorsal horn of the gray matter of the spinal cord, the fiber synapses on the corresponding alpha motor neuron in the ventral horn of the spinal cord. This alpha efferent fiber then exits through the ventral root and courses back sends an action potential to the neuromuscular junction of the original muscle that initiated the reflex to the synapse to cause contraction. This contraction allows the muscle to resist the force that initially caused the reflex. In contrast, the polysynaptic stretch reflex involves a single sensory stimulus that synapses on interneurons within the spinal cord gray matter, which allows communication to multiple muscles for contraction or inhibition.[1][2]

Clinical Significance

These reflexes are graded on a scale from 0 to 4+, where 0 is absent, 2+ is normal, and 4+ indicates hyperactivity wherein a tap elicits a repeating reflex (clonus). Grading these reflexes is important because abnormalities can often indicate that a reflex arc has been affected, which could mean a problem could involve the sensory fiber, the spinal cord, or the motor fiber. If a lesion involves the anterior horn of the spinal cord at that level or the motor fiber itself, then it would be defined as a lower motor neuron lesion (LMN). These lesions result in decreased reflexes (grade 0 to 1) due to damage to the alpha motor neurons. If the lesions involve the cerebral cortex, brain stem, or descending motor tracts, then they are upper motor neuron lesions (UMN). These lesions result in increased reflexes (grade 3 to 4) due to loss of inhibition from the descending motor pathways.[3]

The Hoffman, or 'H reflex,' is similar to muscle stretch reflex and is obtained after the selective electrical stimulation of the sensory 1a afferents; bypassing the muscle spindles.[4]

Higher stimulation should be avoided as it may cause 'F wave' owing to the stimulation of the alpha fibers.

Golgi tendon organs outplay inverse myotatic reflex mediating through the 1b afferents and gamma efferents. This checks sustained tonic contraction following stretch reflex by inhibiting the agonist (inhibitory postsynaptic potentials) and stimulating the corresponding group of antagonists'  muscles (summations of excitatory postsynaptic potentials). Any abnormality in this mechanism leads to hyperexcitable stretch reflexes thereby causing spasticity.[5]

Nursing Actions and Interventions

Under normal circumstances, the monosynaptic reflex is an inducible action, rather than a pathology. However, patients can present with abnormal DTRs from a variety of causes. When pathologic, the monosynaptic reflex provides insight towards an underlying neurological dysfunction; this could indicate a wide variety of etiologies ranging from a spinal cord lesion to an electrolyte imbalance. Thus, identifying or determining the cause of the abnormal reflex could involve many members of the healthcare team, and could improve treatment strategies and management.[6] (Level I) Assessing, discovering, and communicating the presence of an abnormal reflex can enhance patient outcomes, safety, and care. Coordination and communication within the healthcare team of a patient are essential to patient-centered care.[7]

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Monosynaptic Reflex - Questions

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A provider strikes the patient's patellar tendon with a reflex hammer. Which is true of the pathway the physician is assessing?

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Monosynaptic Reflex - References


PERL ER, A comparison of monosynaptic and polysynaptic reflex responses from individual flexor motoneurones. The Journal of physiology. 1962 Dec;     [PubMed]
Iles JF,Roberts RC, Inhibition of monosynaptic reflexes in the human lower limb. The Journal of physiology. 1987 Apr;     [PubMed]
Héroux ME, Tap, tap, who's there? It's localized muscle activity elicited by the human stretch reflex. The Journal of physiology. 2017 Jul 15;     [PubMed]
Palmieri RM,Ingersoll CD,Hoffman MA, The hoffmann reflex: methodologic considerations and applications for use in sports medicine and athletic training research. Journal of athletic training. 2004 Jul     [PubMed]
Thompson AJ,Jarrett L,Lockley L,Marsden J,Stevenson VL, Clinical management of spasticity. Journal of neurology, neurosurgery, and psychiatry. 2005 Apr     [PubMed]
Jensen G,Bar-On E,Wiedler JT,Hautz SC,Veen H,Kay AR,Norton I,Gosselin RA,von Schreeb J, Improving Management of Limb Injuries in Disasters and Conflicts. Prehospital and disaster medicine. 2019 Apr 26     [PubMed]


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